Deutsches Referenzzentrum für Ethik in den Biowissenschaften (DRZE)

Titel: Experimental Animal Models in Musculo-Skeletal Research - Determining the Need for a European Regulation

Termin: 2.2.2006, 9:00 Uhr, bis 3.2.2006, 15:30 Uhr

Veranstaltungsort:
AO Research Institute
Clavadelerstrasse 8
7270 Davos Platz
Switzerland

Referenten: Prof. Dr. Steven Arnoczky (College of Veterinary Medicine, Michigan State University) *** Prof. Dr. Joerg A. Auer (Equine Hospital, Universität Zürich) *** Priv.-Doz. Dr. Regula Bettschart-Wolfensberger (Equine Hospital, Universität Zürich) *** Prof. Dr. Lutz Claes (Insitut für Unfallchirurgische Forschung und Biomechanik, Universitätsklinikum Ulm) *** Prof. Allen Goodship, PhD (Royal College, London) *** Priv.-Doz. Dr. Ralf Müller-Terpitz (Institut für Öffentliches Recht, Universität Bonn) *** Simon Pearce (AO Reseach Institute, AO Foundation, Davos) *** Priv.-Doz. Dr. Brigitte von Rechenberg (Equine Hospital, Universität Zürich) *** Priv.-Doz. Dr. Klaus Peter Rippe (Ethik im Diskurs, Zürich) *** Prof. Dr. Berthold Rittberger (Politikwissenschaft, TU Kaiserslautern)

Weitere Informationen:
http://www.europaeische-akademie-aw.de/susanis/global/download.php/ter ...

Kurzbeschreibung: Animal models are an indispensable part in understanding the human muscoloskeletal system and its diseases. Research on animals is, however, an
expensive and morally sensitive area, so that a considerate and efficient use of animals should guide this kind of research. It turns out that several obstacles impede this goal.

First, there seems to be considerable uncertainty on what animal models are most suitable for studying which human conditions and diseases of the
muscoloskeletal system. The fact that diseases of the human muscoloskeletal system frequently do not match to identical or even only similar diseases in animals draws attention to the need of careful considering the selection of animal models for studying human
diseases.

Second and connected to the first point, the coordination of research efforts between the disciplines of human medicine and veterinary medicine could be improved. The gap between on the one hand the research questions of orthopaedics and traumatology and on the other hand the know-how of veterinarians
concerning animal models sometimes leads to a considerable loss in effectiveness of muscoloskeletal research.

Third, the standards for performing muscoloskeletal research in animals vary widely in Europe and beyond. Apart from the risk of performing research and
developing products that are legally accepted in one country but may cause prosecution in another, this variety of guidelines poses a moral problem: Is it
acceptable that the moral boundaries of using animals in research do differ widely across countries – even those that belong to the same culture group as e.g. the European countries?

The meeting will convene a relatively small group of experts in order to enable an intensive goal-oriented
discussion on the above topics. One of the main aims of this meeting will be to determine whether there is need for further concerted action on behalf of the scientific community. Furthermore, as a result of the meeting, suitable instruments for elaborating recommendations for improving effective and morally acceptable animal research should be suggested.

Kontakt: Europäische Akademie GmbH
Wilhelmstraße 56
53474 Bad Neuenahr-Ahrweiler
Germany
Tel.: +49 - (0)2641 - 97 33 00
Fax: +49 - (0)2641 - 97 33 20
europaeische.akademie@ea-aw.de
http://www.europaeische-akademie-aw.de/

Veranstalter: Europäische Akademie zur Erforschung von Folgen wissenschaftlich-technischer Entwicklungen Bad Neuenahr-Ahrweiler GmbH, AO Research Institute Davos

Wissenschaftliche Leitung: Prof. Dr. Joerg A. Auer (Eqine Hospital, Universität Zürich), Dr. Felix Thiele (Europäische Akademie, Bad Neuenahr-Ahrweiler), Prof. Dr. Erich Schneider (AO Research Institute, Davos)

Schlagworte: Humangenetik, Krankheit, Medizinische Ethik, Tierethik

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