Titel: Lost in the Maze? Navigating Evidence and Ethics in Translational Neuroscience

Termin: 14.2.2018, 13:00 Uhr, bis 16.2.2018, 22:00 Uhr

Veranstaltungsort:
Schloss Herrenhausen
Herrenhäuser Str. 5
30419 Hannover

Referenten: Alison Abbott (Nature Publishing Group/USA) *** Enrica Alteri (European Medicines Agency/UK) *** Christopher Baum (Hannover Medical School/Germany) *** Julie Belluz (Vox.com/USA) *** Annelien Bredenoord (Utrecht University/The Netherlands) *** Virginie Bros-Facer (Eurordis/France) *** Dominique Brossard (University of Wisconsin-Madison/USA) *** Leena Bruckner-Tuderman (Albert-Ludwigs-University of Freiburg and Deutsche Forschungsgemeinschaft/Germany) *** Alex Capron (University of Southern California/USA) *** Timothy Caulfield (University of Alberta/Canada) *** Iain Chalmers (James Lind Initiative/UK) *** Isabelle Clavier (Sanofi/France) *** Katherine Cowan (James Lind Alliance/UK) *** Ulrich Dirnagl (Charité Berlin and Berlin Institute of Health/Germany) *** Cornelius Frömmel (Charité Berlin/Germany) *** Jodi Halpern (University of California Berkeley /USA) *** Insoo Hyun (Case Western Reserve University/USA) *** John Ioannidis (Stanford University/USA) *** Sharon McClellan Thomason (Help 4 HD International) *** Nanette Joyce (University of California Davis/USA) *** Scott Kim (National Institutes of Health/USA) *** Jonathan Kimmelman (McGill University/Canada) *** Paul Knoepfler (University of California Davis/USA) *** Wilhelm Krull (Volkswagen Foundation/Germany) *** Andreas Meyer-Lindenberg (Central Institute of Mental Health/Germany) *** Frank Miedema (University Medical Center Utrecht/The Netherlands) *** Jeffrey Mogil (McGill University/Canada) *** Ubaka Ogbogu (University of Alberta/Canada) *** Sarah Perrault (University of California Davis/USA) *** Laurent Pradier (Sanofi/France) *** Bernard Ravina (Voyager Therapeutics/USA) *** Michael Rieder (Concerned parent, Germany) *** Emily Sena (University of Edinburgh/UK) *** Shai Silberberg (National Institutes of Health/USA) *** Daniel Strech (Hannover Medical School/Germany) *** Thomas Steckler (Janssen Pharmaceutics/Belgium) *** Vicki Wheelock (University of California Davis/USA) *** Hanno Würbel (University of Bern/Switzerland) *** Mark Yarborough (University of California Davis/USA)

Weitere Informationen:
https://www.volkswagenstiftung.de/nc/veranstaltungen/veranstaltungskal ...

Kurzbeschreibung: This Herrenhausen Conference focuses on major scientific and ethical challenges of novel neurological interventions and how they can be overcome. Participants will explore how critically needed trials of new treatment modalities can be launched safely and conducted ethically.
Since most major neurological disorders like Alzheimer's, traumatic brain injuries, Amyothrophic Lateral Sclerosis, and many others have no cure, the despair of patients means they often fail to consider the major risks intrinsic to early clinical trials of novel modalities such as stem cell interventions and gene therapy. While these new pathways to potential treatments need to be pursued, they are being developed in a climate that often is not conducive to good science. Factors such as concerns about irreproducible research results, researchers' needs to divide their time between their research and pursuing funding, and the inflated expectations produced by science hype can all hinder efforts to conduct investigations carefully and responsibly. To help improve this problematic climate, the Herrenhausen Conference will address:

1. The personal despair and public hype that frame contemporary scientific research in neurological disease.
2. Deficiencies in pre-clinical neurological research and how to overcome them in order to increase the safety and predictive value of early trials of novel neurological interventions.
3. Strategies that can improve the informed consent processes for trials of these novel interventions.

The conference will seek clear deliverables to improve the robustness and positive predictive value of pre-clinical research, protect the welfare of research participants, and develop more effective informed consent processes.

We invite all researchers and experts working in this field. There is no fee for the attendance, but registration is essential.

Kontakt: Dr. Oliver Grewe
VolkswagenStiftung
Kastanienallee 35
30519 Hannover
Tel.: +49 (0)511 8381-252
Fax: +49 (0)511 8381-4252
grewe@volkswagenstiftung.de
https://www.volkswagenstiftung.de/

Wissenschaftliche Leitung: Mark Yarborough (University of California Davis, USA), Ulrich Dirnagl (Charité Berlin and Berlin Institute of Health, Germany)

Schlagworte: Hirnforschung